College student Alyssa looks forward to her senior year so she can finally hold her head up high, date a guy and have a "real" college experience after being born with a disabling genetic disorder that affected her smile. Baseball lover Mark plays a high stakes game to get the smile he has always wanted. After struggling with drug addiction, Mark is clean and sober--but will his massive dental surgery force him back on pain medication and jeopardize his sobriety?

An aspiring beautician tries to overcome her extreme fear of dentists and an actress confronts years of shame over her rotting teeth.